Panama, a country of immense cultural diversity and natural beauty, offers a variety of cities that cater to every traveler's taste. From the bustling metropolitan life of Panama City to the serene beaches of Bocas del Toro, each city presents its own unique blend of attractions and experiences. Whether you're looking for adventure, relaxation, or a deep dive into the country's rich history, Panama's cities have something special to offer. Here are nine cities that travelers absolutely love, each providing a distinct flavor of Panamanian life without compromising on safety and enjoyment. Panama City As the capital and largest city of Panama, Panama City is a vibrant metropolis that seamlessly blends the modern with the historic. The city is known for the Panama Canal, an engineering marvel, and the Casco Viejo district, a UNESCO World Heritage site filled with colonial-era landmarks. For a panoramic view of the city and the canal, visit Ancon Hill. Don't miss the BioMuseo, designed by the renowned architect Frank Gehry, which showcases Panama's incredible biodiversity. The Albrook Mall is perfect for shopping enthusiasts, while the Mercado de Mariscos offers fresh seafood and local flavor. When to Visit: The best time to visit Panama City is during the dry season from mid-December to April. The city is less crowded, and the weather is ideal for exploring. The Panama Jazz Festival in January is a fantastic event for music lovers. Travel Tip: Make sure to take a guided tour of the Panama Canal's Miraflores Locks to witness the impressive process of ships passing through the canal. Where to Stay & Eat: Stay at the American Trade Hotel in Casco Viejo for a touch of history or the Waldorf Astoria Panama for modern luxury. For dining, try Maito for innovative Panamanian cuisine or the intimate setting of Restaurante Las Clementinas. Bocas del Toro Bocas del Toro is an archipelago off the Caribbean coast known for its stunning beaches, lush rainforests, and vibrant nightlife. Isla Colón, the main island, is a hub for water sports and eco-tourism. Visit Starfish Beach to see the sea creatures it's named after, and don't miss the opportunity to snorkel or dive in the crystal-clear waters around the Zapatilla Cays. For a cultural experience, the Ngäbe-Buglé community offers insight into the lives of Panama's indigenous peoples. When to Visit: The best time to visit Bocas del Toro is from February to April when the weather is dry and sunny. The Bocas Carnival in February is a lively and colorful celebration worth experiencing. Travel Tip: Take a boat tour to Dolphin Bay in the early morning when the chances of spotting dolphins are higher. Where to Stay & Eat: Consider staying at the eco-friendly Bambuda Lodge or the luxurious Azul Paradise. For dining, El Ultimo Refugio offers fresh seafood with a Caribbean twist, and Café del Mar serves up a great atmosphere and delicious meals. Boquete Nestled in the highlands of Chiriquí, Boquete is known for its cool climate, coffee plantations, and outdoor adventures. The town is a haven for hikers, with trails leading to the Barú Volcano and through the cloud forests where the resplendent quetzal can be spotted. Coffee lovers should not miss a tour of a local coffee farm to taste some of the world's best beans. The Mi Jardín es Su Jardín is a beautiful garden open to the public, offering a peaceful retreat. When to Visit: Visit Boquete between December and March for the best weather. The Flower and Coffee Festival in January is a delightful event showcasing the region's natural and agricultural products. Travel Tip: Experience the thrill of a canopy tour at Boquete Tree Trek, where you can zip line through the treetops and enjoy breathtaking views. Where to Stay & Eat: The Riverside Inn offers cozy accommodations with river views, while Finca Lérida is both a hotel and a coffee estate. For dining, RetroGusto Restaurant & Bar provides an exquisite fusion of local and international flavors, and Colibri Restaurant offers a farm-to-table experience. El Valle de Antón Located in the crater of an extinct volcano, El Valle de Antón is a picturesque town known for its mild climate and natural beauty. Visitors can explore the local market for handicrafts, hike to the Chorro El Macho waterfall, or relax in the thermal hot springs. The Butterfly Haven is a must-visit for nature enthusiasts, and the El Nispero Zoo and Botanical Garden is home to an array of wildlife, including the rare golden frog. When to Visit: The best time to visit El Valle is during the dry season, from December to April. The town is quieter during the weekdays, offering a more relaxed experience. Travel Tip: Don't miss the opportunity to visit the local artisan market on Sundays, where you can find unique souvenirs and fresh produce. Where to Stay & Eat: Los Mandarinos Boutique Spa & Hotel offers luxury accommodations with spa services, and Hotel Campestre provides a family-friendly atmosphere. For dining, Casa de Lourdes offers fine dining in an elegant setting, and Bruschetta Restaurant serves delicious Italian cuisine with a Panamanian twist. Pedasí Pedasí is a small town on the Azuero Peninsula known for its traditional Panamanian culture and beautiful beaches. It's a gateway to the Isla Iguana Wildlife Refuge, a haven for snorkelers and beachgoers. The town itself is charming, with colorful Spanish colonial architecture and a laid-back vibe. Surfing is popular at nearby Playa Venao, and during the months of July to October, visitors can witness sea turtles nesting on the beaches. When to Visit: The ideal time to visit Pedasí is from January to April when the weather is dry. The Carnival in February/March is a vibrant and festive time to experience local traditions. Travel Tip: Take a day trip to Isla Iguana and enjoy the pristine beaches and coral reefs. Make sure to bring your snorkeling gear! Where to Stay & Eat: Stay at the boutique hotel Casa de Campo Pedasi for a comfortable and authentic experience, or enjoy the beachfront location of Villa Marina Lodge. For dining, Restaurante Smiley's offers a friendly atmosphere with live music and great food, while La Huerta serves up fresh, organic meals. Portobelo Portobelo is a historic port town on the Caribbean coast that was once a major hub for Spanish trade. The town is rich in history, with well-preserved forts and the UNESCO-listed San Lorenzo Castle. The Church of San Felipe is home to the famous Black Christ statue, an important religious icon. Portobelo is also a great base for exploring the nearby coral reefs and mangroves, offering excellent opportunities for diving and kayaking. When to Visit: Visit Portobelo between December and April for the best weather conditions. The Festival of the Black Christ on October 21st is a significant cultural event with a large procession and festivities. Travel Tip: Explore the ruins of the Spanish forts for a glimpse into the town's colonial past and enjoy the scenic views of the bay. Where to Stay & Eat: El Otro Lado is a private retreat offering luxury accommodations with a cultural touch. For dining, Captain Jack's Hostel & Restaurant provides a casual setting with a mix of local and international dishes, and Casa Congo offers fresh seafood with a view of the bay. Santa Catalina Santa Catalina is a remote fishing village turned surfers' paradise, known for its world-class waves and laid-back atmosphere. The village is the closest access point to Coiba National Park, a UNESCO World Heritage site with abundant marine life, making it a top destination for divers and snorkelers. The local beaches, such as Playa Estero, are perfect for relaxation and sunbathing. The town has a small selection of restaurants and accommodations, adding to its off-the-beaten-path charm. When to Visit: The dry season from December to April is the best time to visit Santa Catalina for surfing and beach activities. The waves are consistently good, and the weather is sunny. Travel Tip: Even if you're not a surfer, take a surf lesson in Santa Catalina. The town's friendly vibe and excellent instructors make it an ideal place to learn. Where to Stay & Eat: Stay at Hotel Santa Catalina for its beachfront location and surf access, or choose the eco-friendly Sol y Mar for a peaceful retreat. For dining, La Buena Vida offers healthy and delicious meals, and Chano's Point serves up fresh seafood with a view of the waves. David David is the capital of the Chiriquí Province and the third-largest city in Panama. It serves as a commercial center and a gateway to the surrounding highlands and beaches. The city itself has a relaxed pace of life, with a mix of modern amenities and cultural sites. The Miguel de Cervantes Saavedra Park is a central gathering place, and the nearby hot springs of Caldera offer a soothing escape. David is also known for its festivals, including the International Fair of David held in March. When to Visit: The best time to visit David is during the dry season, from December to April. The city's festivals, particularly the International Fair of David, provide a lively atmosphere with exhibitions and cultural performances. Travel Tip: Take a short drive to the Playa La Barqueta for a day at the beach or explore the nearby mountains for hiking and birdwatching. Where to Stay & Eat: Gran Hotel Nacional offers comfortable accommodations with a pool and casino, while Hotel Ciudad de David provides modern amenities in the city center. For dining, Steak House Los Almendros serves high-quality meats, and Restaurante Stylo offers a variety of international dishes. Colon Colon, located on the Caribbean coast near the Atlantic entrance to the Panama Canal, is an important port city with a rich history. The city is undergoing revitalization efforts and features attractions such as the Colon Free Zone, one of the largest duty-free markets in the Americas. Fort San Lorenzo, a UNESCO World Heritage site, offers stunning views and a glimpse into the colonial era. The nearby Gatun Locks provide another perspective on the Panama Canal, and the pristine beaches of Isla Grande are just a short boat ride away. When to Visit: The best time to visit Colon is from January to April, when the weather is dry and pleasant. Avoid the rainy season when the city can experience heavy downpours. Travel Tip: Visit the Gatun Locks early in the morning to avoid crowds and see the canal in action. The Agua Clara Visitor Center offers an excellent view of the expanded locks. Where to Stay & Eat: The Melia Panama Canal offers a luxury stay with historical charm, and Radisson Hotel Colon 2000 provides modern comforts near the free zone. For dining, Restaurante Arrecifes offers fresh seafood, and Café Iguana serves up local and international cuisine in a casual setting. Each of these cities in Panama offers a unique experience, from the hustle and bustle of urban life to the tranquility of beachside towns. When planning your trip, consider the best time to visit based on weather and local events, and don't forget to explore the hidden gems that make each city special. Whether you're indulging in the local cuisine, exploring historical sites, or enjoying the natural beauty, Panama's cities are sure to leave a lasting impression.